Imp-1/crd-bp function

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Witrynapreferentially to distinct CRD-BP KH domains. The novel insights revealed in this study have important implications on the understanding of the oncogenic mechanism of CRD-BP a well as in the future design of inhibitors against CRD-BP function. Coding region determinant-binding protein (CRD-BP; mouse), also known as IMP1 (human), Witryna25 maj 2007 · CRD-BP/IMP-1 expression in HCT116 colon cancer cells (a) and adult human colon (b–e).Immunohistochemistry was performed as described in the Material and methods section by either using a rabbit anti-CRD-BP/IMP1 antibody (a and e), or by using a goat anti CRD-BP/IMP-1 antibody (b–d).In normal mucosa (b, d, e) CRD …

CRD-BP shields c-myc and MDR-1 RNA from endonucleolytic …

Witryna15 cze 2006 · CRD-BP function seems to be important for the pathogenesis of human colorectal ... P. et al. C-MYC and IGF-II mRNA-binding protein (CRD-BP/IMP-1) in … Witryna5 maj 2008 · Inhibition of β-TrCP function sensitizes human ... (2001). C-MYC and IGF-II mRNA-binding protein (CRD-BP/IMP-1) in benign and malignant mesenchymal tumors. ... (2007). CRD-BP shields c-myc and ... songs that use assonance

CRD-BP - Wikiwand

WitrynaPlasmid pMSCV PIG IMP-1-short from Dr. David Bartel's lab contains the insert IGF-II mRNA-binding protein 1 and is published in Cell. 2009 Aug 21. 138(4):673-84. ... Function; Biosensors; Chemogenetics; … WitrynaInsulin -like growth factor II mRNA-binding protein, CRD-BP, VICKZ1), IMP-2 (IMP2, VICKZ2, p62) and IMP-3 (KOC1, VICKZ3), contain a unique combination of RNA recognition motifs and four hnRNP K homology domains. IMP-1 is abundant in embryonal tissues and in 81% of colon cancers, 58.5% of breast songs that use genius of love beat

Targeted Knockdown of the RNA-binding Protein CRD-BP …

(PDF) CRD-BP mediates stabilization of TrCP1 and c-myc

WitrynaPlasmid pIS1 IMP-1 long UTR from Dr. David Bartel's lab contains the insert IGF-II mRNA-binding protein 1 UTR and is published in Cell. 2009 Aug 21. 138(4):673-84. ... (a.k.a. CRD-BP, CRDBP, IMP-1, IMP1, VICKZ1, ZBP1) ... Long means that all functional alternative polyadenylation signals have been deleted. WitrynaCRD-BP (mouse) are orthologous and paralogous members ... To characterize the cellular functions of the IMPs, we performed a loss-of-function study of IMP1 and … songs that use melismaWitryna31 sty 2007 · CRD-BP protects the c-myc CRD and MDR-1 RNA from cleavage by the mammalian endoribonuclease. Having established that recombinant CRD-BP can bind c-myc CRD and MDR-1 RNA, we then sought to determine if the binding of CRD-BP to RNA could directly protect these transcripts from degradation by an endoribonuclease … small garden birds identification

"Witryna15 cze 2006 · CRD-BP function seems to be important for the pathogenesis. of human colorectal cancer, a disease in which the activation of. b ... (CRD-BP/IMP-1) in benign and malignant mesenchymal tumors. Int. J. " - Imp-1/crd-bp function

Imp-1/crd-bp function

Regulation of RNA-binding by KH domains of CRD-BP - CORE

Witryna1 paź 2010 · Europe PMC is an archive of life sciences journal literature. Introduction. CRD-BP, the coding region determinant binding protein, also known as insulin-like growth factor 2 mRNA-binding protein 1 (IMP-1 or IGF2BP-1), is a multifunctional RNA binding protein involved in different processes such as mRNA turnover, translation control, … WitrynaCRD-BP belongs to a family of RNA binding proteins that show close a relation to the chicken β-actin zipcode-binding protein ZBP1[1] and the human forms of the protein …

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Witryna19 lis 2004 · Thus, we have identified a dominant function for CRD-BP in cell proliferation of human K562 cells, involving a possible IGF-II-dependent mechanism … Witryna10 paź 2016 · CRD-BP, the coding region determinant binding protein, also known as insulin-like growth factor 2 mRNA-binding protein 1 (IMP-1 or IGF2BP-1), is a multifunctional RNA binding protein involved in different processes such as mRNA turnover, translation control, and localization.

Witryna15 lis 2001 · IMP-1/CRD-BP was detected in 73% of malignant mesenchymal and 40% of benign mesenchymal tumours and high expression was found in all 14 Ewing's sarcoma [59]. Gene amplification of CRD-BP has been ... Witryna15 cze 2006 · CRD-BP function seems to be important for the pathogenesis of human colorectal ... P. et al. C-MYC and IGF-II mRNA-binding protein (CRD-BP/IMP-1) in benign and malignant mesenchymal tumors. Int. ...

WitrynaIMP-1 Recombinant Protein (Cat. No. 39-901) has been validated for use in E and WB. ... ZBP1, CRDBP, IMP-1, CRD-BP, VICKZ1, Insulin-like growth factor 2 mRNA-binding protein 1, Coding region determinant ... The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". cookielawinfo … WitrynaIMP-1 Recombinant Protein (Cat. No. 39-901) has been validated for use in E and WB. ... ZBP1, CRDBP, IMP-1, CRD-BP, VICKZ1, Insulin-like growth factor 2 mRNA-binding …

Witryna15 cze 2006 · It is shown that β-catenin stabilizes the mRNA encoding the F-box protein βTrCP1, and the RNA-binding protein CRD-BP is identified as a previously unknown …

WitrynaPlasmid pIS1 IMP-1 long UTR from Dr. David Bartel's lab contains the insert IGF-II mRNA-binding protein 1 UTR and is published in Cell. 2009 Aug 21. 138(4):673-84. ... songs that use major 7th chordsWitryna29 sie 2024 · Introduction. Insulin-like growth factor II mRNA-binding protein 1 (IGF2BP1/IMP1), also known as the c-Myc coding region determinant-binding protein (CRD-BP) and zipcode-binding protein 1 (ZBP1), is a multifunctional RNA-binding protein that binds to diverse cancer-associated mRNAs to promote mRNA stability, … small garden bench with storageWitryna6 paź 2001 · CRD‐BP/IMP‐1 belongs to a family of RNA‐binding proteins containing 2 RRMs and 4 KH domains; it plays a role in the posttranscriptional control of both … small garden building offering shade and restWitryna25 maj 2007 · CRD-BP/IMP-1 expression in HCT116 colon cancer cells (a) and adult human colon (b–e).Immunohistochemistry was performed as described in the Material and methods section by either using a rabbit anti-CRD-BP/IMP1 antibody (a and e), or by using a goat anti CRD-BP/IMP-1 antibody (b–d).In normal mucosa (b, d, e) CRD … songs that use pathosWitryna9 paź 2013 · High levels of CRD-BP that are found in primary human colorectal tumours exhibiting active beta-catenin/Tcf signalling implicates CRD-BP induction in the upregulation of beta TrCP1, in the ... songs that use panningWitryna7 sty 2011 · CRD-BP was shown to upregulate the expression of different genes including c-myc, 13 β-TrCP1, 10 MDR1, 14 and GLI1. 15 It was also shown to be necessary for proper cell adhesion, cytoplasmic spreading, and invadopodia formation through its binding to the 3′UTR of CD44 mRNA and stabilization of the mRNA. In … songs that use literary devicesWitrynaPlasmid pMSCV PIG IMP-1-long-mut from Dr. David Bartel's lab contains the insert IGF-II mRNA-binding protein 1 and is published in Cell. 2009 Aug 21. 138(4):673-84. ... (a.k.a. CRD-BP, CRDBP, IMP-1, IMP1, VICKZ1, ZBP1) ... Long means that all functional alternative polyadenylation signals have been deleted. small garden bench seat