WebMar 19, 2024 · Purpose of Review Aside from absolute indications, the optimal timing of renal replacement therapy (RRT) in critical care is unknown. In this review, we discuss initiation of RRT in relation to both severity of acute kidney injury (AKI) and fluid accumulation. Recent Findings Results from studies of early vs. late RRT are … WebMay 31, 2024 · Patients were randomised to receive early RRT within 8 h, or late therapy starting more than 12 h after the patient had reached KDIGO stage 3 AKI criteria. Mortality at 90 days was lower in the early group (39.3% vs 54.7%, p = 0.03), and all-cause mortality remained significantly lower at 1 year (50.2% early vs 69.8% delayed; p = 0.01) [ 12 ].
Early versus late initiation of renal replacement …
WebMay 1, 2024 · The primary outcome of mortality at 90 days did not differ between patients who received early versus late initiation of RRT (58% vs. 54%; P = 0.38). Furthermore, no benefits were seen from early initiation of RRT in secondary outcomes. Results of previous larger studies were conflicting, Infact, one major trial (ELAIN) showed a 90-day ... WebOct 24, 2024 · The pooled RR for short-term mortality for early versus late initiation of RRT was 0.99 (95% CI 0.84–1.17, p = 0.93, I 2 = 44%). The TSA for the primary outcome showed a required information size was not … fish point michigan
impact of early versus late initiation of renal replacement …
WebConclusion: There is no added benefit of early initiation of RRT in patient with AKI; this may lead to treatment-emergent adverse events. Delaying the initiation of RRT with close … WebOct 24, 2024 · The pooled RR for short-term mortality for early versus late initiation of RRT was 0.99 (95% CI 0.84–1.17, p = 0.93, I 2 = 44%). The TSA for the primary outcome showed a required information size was not … WebIntroduction: Our aim was to investigate the impact of early versus late initiation of renal replacement therapy (RRT) on clinical outcomes in critically ill patients with acute kidney injury (AKI). Methods: Systematic review and meta-analysis were used in this study. PUBMED, EMBASE, SCOPUS, Web of Science and Cochrane Central Registry of … candied cinnamon cucumbers