Cyclophosphamide (CP), also known as cytophosphane among other names, is a medication used as chemotherapy and to suppress the immune system. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and … See more Cyclophosphamide is used to treat cancers and autoimmune diseases. It is used to quickly control the disease. Due to its toxicity, it is replaced as soon as possible by less toxic drugs. Regular and frequent laboratory … See more Like other alkylating agents, cyclophosphamide is teratogenic and contraindicated in pregnant women (pregnancy category D) except for life-threatening … See more Oral cyclophosphamide is rapidly absorbed and then converted by mixed-function oxidase enzymes (cytochrome P450 system) in the liver to active metabolites. The main active metabolite is 4-hydroxycyclophosphamide, which exists in See more As reported by O. M. Colvin in his study of the development of cyclophosphamide and its clinical applications, Phosphoramide mustard, one of the principal toxic metabolites of cyclophosphamide, was synthesized and reported by … See more Adverse drug reactions from cyclophosphamide are related to the cumulative medication dose and include chemotherapy-induced nausea and vomiting, bone marrow suppression, stomach ache, hemorrhagic cystitis, diarrhea, … See more The main effect of cyclophosphamide is due to its metabolite phosphoramide mustard. This metabolite is only formed in cells that have low levels of ALDH. Phosphoramide mustard forms DNA crosslinks both between and within DNA strands at See more The abbreviation CP is common, although abbreviating drug names is not best practice in medicine. See more WebCyclophosphamide, formerly known as cytophosphane among other, is used as chemotherapy and to suppress the immune system. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. As an immune suppressor it is used in nephrotic …
Cytophosphane drug & pharmaceuticals. Available Forms, Doses, …
Webcyclophosphamide Uses - commonly prescribed nitrogen mustard - used alone or in combo with other drugs against a wide variety of cancers including: Hodgkin's disease, lymphoma, multiple myeloma, breast cancer, ovarian cancer - one of only a few ca drugs that are well absorbed when given orally WebSep 19, 2024 · Cyclophosphamide induces apoptosis of activated T cells and abatacept (CTLA4Ig) blocks activation of T cells by inhibiting the co-stimulatory signal. Compared to the standard-of-care control arm, the experimental arm is much more convenient and expected to be associated with fewer toxicities. canfield music on the green
Cytophosphane Uses, Dosage, Side Effects, FAQ - MedicinesFAQ
WebCytophosphane (C₇H₁₅Cl₂N₂O₂P), also known as Cyclophosphamide, is a medication used as chemotherapy and to suppress the immune system. MOLEK-SYNTEZ is a puzz... Web시클로포스파미드 ( cyclophosphamide, CP, 다른 이름: cytophosphane 등) [1] 는 화학요법 으로서, 또 면역억제제 로서 사용되는 약물이다. [2] 화학 요법으로서 림프종, 다발성 골수종, 백혈병, 난소암, 유방암, 소세포폐암, 신경모세포종, 육종 을 치료하기 위해 사용된다. [2] 면역 억제제로서 신증후군, 다발성 맥관염 동반 육아종, 그리고 잇따르는 장기 이식 및 기타 … WebCyclophosphamide, commonly known as cytophosphane or cytophosphane, is a therapeutic modality that also suppresses the immune function. Lymphoma, multiple … canfield name origin