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Blimp1 glycosylation

WebOct 15, 2012 · Stress in the endoplasmic reticulum (ER) triggers the unfolded protein response (UPR), a signaling mechanism that allows cellular adaptation to ER stress by engaging pro-adaptive transcription factors and alleviating protein folding demand. One such transcription factor, X-box binding protein (XBP1), originates from the inositol-requiring … WebSep 28, 2012 · Primordial germ cells (PGCs) sequentially induce specific genes required for their development. We focused on epigenetic changes that regulate PGC-specific gene expression. mil-1, Blimp1, and Stella are preferentially expressed in PGCs, and their expression is upregulated during PGC differentiation. Here, we first determined DNA …

Conserved and Unique Functions of Blimp1 in Immune Cells

WebOct 12, 2024 · Plasma cells also require a high rate of glucose uptake for glycolysis and … WebJun 2, 2024 · Glycosylation is an important posttranslational modification that covalently … biots respiratory breathing is a sign of what https://digiest-media.com

Conserved and Unique Functions of Blimp1 in Immune Cells

WebMW performed most experiments, TP performed the flow-cytometric analyses of unimmunized PCs, the intracellular staining of IgM expression and the Blimp1 rescue experiments, PB performed the Xbp1 ChIP-seq experiment, AH and JS performed the glycosylation analysis, DK-P generated the Xbp1 Bio/+ mouse, SK generated the … WebOct 30, 2024 · In mammals, Blimp1 (B lymphocyte-induced maturation protein 1) encoded by the prdm1 gene and its homolog Hobit (homolog of Blimp1 in T cells) encoded by znf683, represent key transcriptional … WebFeb 12, 2024 · Blimp1 negatively regulates IL-6- and STAT3-dependent Dnmt3a … biots pronunciation

Precocious expression of Blimp1 in B cells causes …

Category:Regulatory network of BLIMP1, IRF4, and XBP1 triad in plasmacytic ...

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Blimp1 glycosylation

Overexpression of transcription factor BLIMP1/prdm1 leads to …

WebMar 1, 2014 · The transcriptional repressor B lymphocyte-induced maturation protein 1 … WebMar 1, 2005 · In plasma cells, BLIMP1 (B-lymphocyte-induced maturation protein 1), XBP1 (X-box-binding protein 1) and IRF4 (interferon-regulatory factor 4) are important: they repress the B-cell gene-expression ...

Blimp1 glycosylation

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WebView Mouse Monoclonal anti-BLIMP1/PRDM1 Antibody (3H2-E8) [FITC] (NB600-235F). … WebSDS-Page: Recombinant Human BLIMP1/PRDM1 Protein [H00000639-Q01] - 12.5% SDS-PAGE Stained with Coomassie Blue. Product Details. Summary. Reactivity: Hu Species Glossary: ... Glycosylation : Research Areas for BLIMP1/PRDM1 Partial Recombinant Protein (H00000639-Q01) Find related products by research area. Cancer; …

http://www.globalauthorid.com/WebPortal/AuthorView?wd=GAID10160321&rc=6A62E4 WebJan 30, 2024 · A hallmark of Niemann-Pick disease, type C (NPC) is the progressive …

WebDec 22, 2024 · Transcription factor Blimp1 identified as potential target for modulating T … WebApr 15, 2009 · Blimp1 associates with a multitude of chromatin modifying enzymes inducing epigenetic changes at specific targets to regulate these diverse cell fates. In this review, we focus on the novel and emerging roles of Blimp1 in multiple tissues, on mechanisms of transcriptional repression by Blimp1 and on the activity of Blimp1 as a tumor suppressor.

WebOct 1, 2024 · BLIMP1 is a transcriptional repressor as its ectopic expression extinguishes …

WebFeb 21, 2006 · Biallelic inactivation of BLIMP1 by rearrangement and deletion in the Ly3 cell line. (A) BLIMP1 genomic locus: filled and empty boxes represent coding and noncoding exons, respectively. Arrows correspond to alternative transcription initiation sites, and triangles below the map depict the primers used for mutational analysis. biotta balance wocheAs a potent repressor of beta-interferon (IFN-β), BLIMP-1 competes for interferon regulatory factors (IRF) binding sites in the IFN-β promoter due to its sequence similarity with IRF1 and IRF2. However, BLIMP-1 cools down and activates immune responses in a highly contextual manner. BLIMP-1 represses NFκB/TNF-R pathway repressor NLRP12, thus indirectly activating the immun… biots vs cheyne-stokesWebOct 30, 2024 · In mammals, Blimp1 (B lymphocyte-induced maturation protein 1) … dale chihuly educationWebAbstract. The gene encoding the human BLIMP1, prdm1, is located on chromosome 6q21, a locus frequently deleted in lymphoid tumors. BLIMP1 is able to silence its target genes in a context-dependent manner through different mechanisms. BLIMP1 is expressed in both B and T cells, in which it plays important functions. dale chihuly exhibits 2023WebMar 21, 2024 · Glycosylation from GlyGen 1 site, 1 O-linked glycan (1 site) Other … biotta ingwerWebSep 1, 2024 · Overexpression of transcription factor BLIMP1/prdm1 leads to growth … biot strain tensorWebFeb 5, 2024 · Blimp1 is a central regulator of early plasma cell ... NP-specific B cells reveal significant enrichment for genes that encode … biotta bio preiselbeer plus saft